Sitagliptin, new investigational treatment for type 2 diabetes, may offer new hope for patients

In the Phase II be taught of greater than 1,000 patients, ''sitagliptin'', Merck Sharp & Dohme's investigational prescription from a untried perspective of diabetes use call dipeptidyl peptidase 4 (DPP-4) inhibitors, first-class glycaemic sway surrounded with patients next to sort 2 diabetes and exhibit a haven and tolerability profile akin to placebo. In enhancement, patients taking sitagliptin earthly knowledgeable no decisive bulk gain and a feathers hazard of hypoglycaemia.

"Results from the studies conduct to date be atrociously potential," said Peter Stein, Senior Director in Clinical Research, Metabolism, Merck Research Laboratories, Rahway, NJ, USA. "The specifications all for capably adopt therapy which bring about improved glycaemic control than settled therapies be well certain and we are contender that these short-term clinical studies acquaint notes of notion for sitagliptin, offering a new sureness for type 2 diabetes patients. Ongoing Phase III trial should deliver greater acuity into the efficacy and tolerability profile of sitagliptin done a longer event of time".

The longer term end of children born to mothers with epilepsy J Neurol Neurosurg Psychiatry 2004: 75:1575-83 Editorial: The longer term outcome of children born to mothers with epilepsy J Neurol Neurosurg Psychiatry 2004; 75: 1517-9 Contacts: Paper: Professor David Chadwick, Walton Centre for Neurology and Neurosurgery, Liverpool, UK.

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